InterPregGen: genetic studies of pre-eclampsia in three continents.


Morgan, L; McGinnis, R; Steinthorsdottir, V; Svyatova, G; Zakhidova, N; Lee, WK; Iversen, AC; Magnus, P; Walker, J; Casas, JP; Sultanov, S; Laivuori, H; (2014) InterPregGen: genetic studies of pre-eclampsia in three continents. Norsk epidemiologi = Norwegian journal of epidemiology, 24 (1-2). pp. 141-146. ISSN 0803-2491

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Abstract

Pre-eclampsia is a major cause of maternal and fetal mortality in pregnancy. The identification of genetic variants which predispose to pre-eclampsia demands large DNA collections from affected mothers and babies and controls, with reliable supporting phenotypic data. The InterPregGen study has assembled a consortium of researchers from Europe, Central Asia and South America with the aim of elucidating the genetic architecture of pre-eclampsia. The MoBa collection is playing a vital role in this collaborative venture, which has the potential to provide new insights into the causes of pre-eclampsia, and provide a rational basis for novel approaches to prevention and treatment.

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
Research Centre: Centre for Maternal, Reproductive and Child Health (MARCH)
PubMed ID: 26568652
URI: http://researchonline.lshtm.ac.uk/id/eprint/2373877

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