MICROSCOPIC-OBSERVATION DRUG-SUSCEPTIBILITY (MODS) FOR RAPID DIAGNOSIS OF LYMPH NODE TUBERCULOSIS AND DETECTION OF DRUG RESISTANCE.


Kirwan, DE; Ugarte-Gil, C; Gilman, RH; Caviedes, L; Rizvi, SM; Ticona, E; Chavez, G; Cabrera, JL; Matos, ED; Evans, CA; Moore, DA; Friedland, JS; Lymph Node TB Working Group Peru., ; (2015) MICROSCOPIC-OBSERVATION DRUG-SUSCEPTIBILITY (MODS) FOR RAPID DIAGNOSIS OF LYMPH NODE TUBERCULOSIS AND DETECTION OF DRUG RESISTANCE. Journal of clinical microbiology. ISSN 0095-1137 DOI: 10.1128/JCM.02227-15

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Abstract

In the study, 132 patients with lymphadenopathy were investigated. 52 (39.4%) were diagnosed with TB. MODS provided rapid (13 days), accurate diagnosis (sensitivity 65.4%), and reliable DST. Despite lower sensitivity than other methods, faster results and simultaneous DST are advantageous in resource-poor settings, supporting incorporation of MODS into diagnostic algorithms for extrapulmonary TB.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Research Centre: Antimicrobial Resistance Centre (AMR)
TB Centre
PubMed ID: 26511739
Web of Science ID: 367537600033
URI: http://researchonline.lshtm.ac.uk/id/eprint/2338141

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