Comparison of previous and present World Health Organization clinical staging criteria in HIV-infected Malawian children
Poerksen, G; Nyirenda, M; Pollock, L; Blencowe, H; Tembo, P; Chesshyre, E; Jefferis, O; Kenny, J; Moons, P; Bunn, J; Molyneux, E; (2009) Comparison of previous and present World Health Organization clinical staging criteria in HIV-infected Malawian children. AIDS (London, England), 23 (14). pp. 1913-6. ISSN 0269-9370 DOI: 10.1097/QAD.0b013e32832f7b39Full text not available from this repository.
In many settings, HIV infected children are looked after with limited access to CD4 cell count or viral load. The decision to initiate antiretroviral therapy (ART) is made clinically, based on the WHO paediatric staging criteria, which were revised in 2006. Results of using new and old criteria were compared. Of 694 children, 626 (90.2%) fulfilled criteria to start ART when applying the new WHO staging guidelines, whereas 330 (47.6%) children were eligible for ART when using the old WHO criteria. This signifies a marked rise in the number of paediatric patients qualifying for ART on clinical grounds.
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