Data Resource Profile: Clinical Practice Research Datalink (CPRD).


Herrett, E; Gallagher, AM; Bhaskaran, K; Forbes, H; Mathur, R; van Staa, T; Smeeth, L; (2015) Data Resource Profile: Clinical Practice Research Datalink (CPRD). International journal of epidemiology, 44 (3). pp. 827-36. ISSN 0300-5771 DOI: 10.1093/ije/dyv098

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Abstract

: The Clinical Practice Research Datalink (CPRD) is an ongoing primary care database of anonymised medical records from general practitioners, with coverage of over 11.3 million patients from 674 practices in the UK. With 4.4 million active (alive, currently registered) patients meeting quality criteria, approximately 6.9% of the UK population are included and patients are broadly representative of the UK general population in terms of age, sex and ethnicity. General practitioners are the gatekeepers of primary care and specialist referrals in the UK. The CPRD primary care database is therefore a rich source of health data for research, including data on demographics, symptoms, tests, diagnoses, therapies, health-related behaviours and referrals to secondary care. For over half of patients, linkage with datasets from secondary care, disease-specific cohorts and mortality records enhance the range of data available for research. The CPRD is very widely used internationally for epidemiological research and has been used to produce over 1000 research studies, published in peer-reviewed journals across a broad range of health outcomes. However, researchers must be aware of the complexity of routinely collected electronic health records, including ways to manage variable completeness, misclassification and development of disease definitions for research.<br/>

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
Faculty of Epidemiology and Population Health > Dept of Population Health (2012- ) > Dept of Population Studies (1974-2012)
Faculty of Epidemiology and Population Health > Dept of Population Health (2012- )
Research Centre: EHR Research Group
PubMed ID: 26050254
Web of Science ID: 359702200017
URI: http://researchonline.lshtm.ac.uk/id/eprint/2210805

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