The complex evolution of antibiotic resistance in Mycobacterium tuberculosis.
Fonseca, JD; Knight, GM; McHugh, TD; (2015) The complex evolution of antibiotic resistance in Mycobacterium tuberculosis. International journal of infectious diseases , 32. pp. 94-100. ISSN 1201-9712 DOI: 10.1016/j.ijid.2015.01.014
Multidrug-resistant and extensively drug-resistant tuberculosis (TB) represent a major threat to the control of the disease worldwide. The mechanisms and pathways that result in the emergence and subsequent fixation of resistant strains of Mycobacterium tuberculosis are not fully understood and recent studies suggest that they are much more complex than initially thought. In this review, we highlight the exciting new areas of research within TB resistance that are beginning to fill these gaps in our understanding, whilst also raising new questions and providing future directions.
|Faculty and Department:||Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology|
|Research Centre:||Antimicrobial Resistance Centre (AMR)|
|Web of Science ID:||352401500016|
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