Impact of bleeding on mortality after percutaneous coronary intervention results from a patient-level pooled analysis of the REPLACE-2 (randomized evaluation of PCI linking angiomax to reduced clinical events), ACUITY (acute catheterization and urgent intervention triage strategy), and HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trials.


Mehran, Roxana; Pocock, Stuart; Nikolsky, Eugenia; Dangas, George D; Clayton, Tim; Claessen, Bimmer E; Caixeta, Adriano; Feit, Frederick; Manoukian, Steven V; White, Harvey; Bertrand, Michel; Ohman, E Magnus; Parise, Helen; Lansky, Alexandra J; Lincoff, A Michael; Stone, Gregg W; (2011) Impact of bleeding on mortality after percutaneous coronary intervention results from a patient-level pooled analysis of the REPLACE-2 (randomized evaluation of PCI linking angiomax to reduced clinical events), ACUITY (acute catheterization and urgent intervention triage strategy), and HORIZONS-AMI (harmonizing outcomes with revascularization and stents in acute myocardial infarction) trials. JACC. Cardiovascular interventions, 4 (6). pp. 654-64. ISSN 1876-7605

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Abstract

Non-CABG-related bleeding within 30 days is strongly associated with an increased risk of subsequent mortality at 1 year in patients undergoing PCI for all indications. A risk score was established to calculate the bleeding risk for patients undergoing PCI, allowing therapeutic decision making to minimize the incidence of bleeding.

Item Type: Article
PubMed ID: 21700252
URI: http://researchonline.lshtm.ac.uk/id/eprint/20523

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