'Team up against TB': promoting involvement in Thibela TB, a trial of community-wide tuberculosis preventive therapy.

Grant, AD; Coetzee, L; Fielding, KL; Lewis, JJ; Ntshele, S; Luttig, MM; Mngadi, KT; Muller, D; Popane, F; Mdluli, J; Mngadi, N; Sefuthi, C; Clark, DA; Churchyard, G; (2010) 'Team up against TB': promoting involvement in Thibela TB, a trial of community-wide tuberculosis preventive therapy. AIDS (London, England), 24 Suppl 5. S37-44. ISSN 0269-9370 DOI: https://doi.org/10.1097/01.aids.0000391020.10661.eb

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OBJECTIVE: To describe a programme of community education and mobilization to promote uptake in a cluster-randomized trial of tuberculosis preventive therapy offered to all members of intervention clusters. SETTING AND PARTICIPANTS: Gold mines in South Africa, where tuberculosis incidence is extremely high, despite conventional control measures. All employees in intervention clusters (mine shaft and associated hostel) were invited to enrol. MAIN OUTCOME MEASURE: Cumulative enrolment in the study in intervention clusters. RESULTS: Key steps in communicating information relevant to the study included extensive consultation with key stakeholders; working with a communication company to develop a project 'brand'; developing a communication strategy tailored to each intervention site; and involving actors from a popular television comedy series to help inform communities about the study. One-to-one communications used peer educators along with study staff, and participant advisory groups facilitated two-way communication between study staff and participants. By contrast, treatment 'buddies' and text messaging to promote adherence proved less successful. Mean cumulative enrolment in the first four intervention clusters was 61.9%, increasing to 83.0% in the final four clusters. CONCLUSION: A tailored communication strategy can facilitate a high level of enrolment in a community health intervention.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Centre for Evaluation
TB Centre
Tropical Epidemiology Group
PubMed ID: 21079426
Web of Science ID: 284823400006
URI: http://researchonline.lshtm.ac.uk/id/eprint/2035


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