Childhood diarrhoeal deaths in seven low- and middle-income countries.


Rahman, AE; Moinuddin, M; Molla, M; Worku, A; Hurt, L; Kirkwood, B; Mohan, SB; Mazumder, S; Bhutta, Z; Raza, F; Mrema, S; Masanja, H; Kadobera, D; Waiswa, P; Bahl, R; Zangenberg, M; Muhe, L; Persistent Diarrhoea Research Group; (2014) Childhood diarrhoeal deaths in seven low- and middle-income countries. Bulletin of the World Health Organization, 92 (9). pp. 664-71. ISSN 0042-9686 DOI: 10.2471/BLT.13.134809

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Abstract

To investigate the clinical characteristics of children who died from diarrhoea in low- and middle-income countries, such as the duration of diarrhoea, comorbid conditions, care-seeking behaviour and oral rehydration therapy use. The study included verbal autopsy data on children who died from diarrhoea between 2000 and 2012 at seven sites in Bangladesh, Ethiopia, Ghana, India, Pakistan, Uganda and the United Republic of Tanzania, respectively. Data came from demographic surveillance sites, randomized trials and an extended Demographic and Health Survey. The type of diarrhoea was classified as acute watery, acute bloody or persistent and risk factors were identified. Deaths in children aged 1 to 11 months and 1 to 4 years were analysed separately. The proportion of childhood deaths due to diarrhoea varied considerably across the seven sites from less than 3% to 30%. Among children aged 1-4 years, acute watery diarrhoea accounted for 31-69% of diarrhoeal deaths, acute bloody diarrhoea for 12-28%, and persistent diarrhoea for 12-56%. Among infants aged 1-11 months, persistent diarrhoea accounted for over 30% of diarrhoeal deaths in Ethiopia, India, Pakistan, Uganda and the United Republic of Tanzania. At most sites, more than 40% of children who died from persistent diarrhoea were malnourished. Persistent diarrhoea remains an important cause of diarrhoeal death in young children in low- and middle-income countries. Research is needed on the public health burden of persistent diarrhoea and current treatment practices to understand why children are still dying from the condition. Abstract available from the publisher. Abstract available from the publisher. Abstract available from the publisher. Abstract available from the publisher. Abstract available from the publisher.

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Population Health (2012- ) > Dept of Nutrition and Public Health Interventions Research (2003-2012)
Faculty of Epidemiology and Population Health > Dept of Population Health (2012- )
Research Centre: Centre for Maternal, Reproductive and Child Health (MARCH)
Maternal and Child Health Intervention Research Group
PubMed ID: 25378757
Web of Science ID: 342719000010
URI: http://researchonline.lshtm.ac.uk/id/eprint/2021064

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