Arm-in-cage testing of natural human-derived mosquito repellents.


Logan, JG; Stanczyk, NM; Hassanali, A; Kemei, J; Santana, AE; Ribeiro, KA; Pickett, JA; Mordue Luntz, AJ; (2010) Arm-in-cage testing of natural human-derived mosquito repellents. Malar J, 9. p. 239. ISSN 1475-2875 DOI: https://doi.org/10.1186/1475-2875-9-239

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Abstract

Individual human subjects are differentially attractive to mosquitoes and other biting insects. Previous investigations have demonstrated that this can be attributed partly to enhanced production of natural repellent chemicals by those individuals that attract few mosquitoes in the laboratory. The most important compounds in this respect include three aldehydes, octanal, nonanal and decanal, and two ketones, 6-methyl-5-hepten-2-one and geranylacetone [(E)-6,10-dimethylundeca-5,9-dien-2-one]. In olfactometer trials, these compounds interfered with attraction of mosquitoes to a host and consequently show promise as novel mosquito repellents.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
Research Centre: Malaria Centre
PubMed ID: 20727149
Web of Science ID: 282416500001
URI: http://researchonline.lshtm.ac.uk/id/eprint/1753

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