Physical activity and cause-specific mortality in men: further evidence from the Whitehall study


Batty, GD; Shipley, MJ; Marmot, M; Smith, GD; (2001) Physical activity and cause-specific mortality in men: further evidence from the Whitehall study. European journal of epidemiology, 17 (9). pp. 863-9. ISSN 0393-2990

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Abstract

Reports of studies relating physical activity to stroke and cancer sub-types indicate inconsistent findings. Some are hampered by low statistical power, owing to a low number of events, and a failure to adjust for potential confounding variables. The purpose of this study was to relate physical activity to 12 mortality endpoints in a prospective cohort study of 11,663 men aged 40-64 years who responded to an enquiry about travel activity during a baseline medical examination conducted between 1967 and 1969. During 25 years of follow-up there were 4672 deaths. Travel activity was inversely related to mortality attributable to all-causes, coronary heart disease, respiratory disease and lung cancer, whereas the association with stroke was positive. There was evidence for attenuation of some of these associations on adjustment for potentially confounding variables. Our simplistic measure of physical activity may, in part, explain the weak associations seen.

Item Type: Article
Keywords: Adult, Cause of Death, Cerebrovascular Accident/mortality, Coronary Disease/mortality, England/epidemiology, Human, Male, Middle Age, Mortality/*trends, Proportional Hazards Models, Prospective Studies, Regression Analysis, Respiratory Tract Diseases/mortality, Risk Factors, Support, Non-U.S. Gov't, *Travel, Adult, Cause of Death, Cerebrovascular Accident, mortality, Coronary Disease, mortality, England, epidemiology, Human, Male, Middle Age, Mortality, trends, Proportional Hazards Models, Prospective Studies, Regression Analysis, Respiratory Tract Diseases, mortality, Risk Factors, Support, Non-U.S. Gov't, Travel
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
PubMed ID: 12081106
Web of Science ID: 175804500010
URI: http://researchonline.lshtm.ac.uk/id/eprint/17474

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