Anopheline vectors and malaria transmission in eastern Afghanistan


Rowland, M; Mohammed, N; Rehman, H; Hewitt, S; Mendis, C; Ahmad, M; Kamal, M; Wirtz, R; (2002) Anopheline vectors and malaria transmission in eastern Afghanistan. Transactions of the Royal Society of Tropical Medicine and Hygiene, 96 (6). pp. 620-6. ISSN 0035-9203 DOI: https://doi.org/10.1016/S0035-9203(02)90331-7

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Abstract

Anopheline vectors and malaria transmission were studied in 2 river-irrigated, rice-growing districts of eastern Afghanistan from May 1995 to December 1996. Clinical malaria was monitored in 12 rural villages (population 14,538) by passive case detection at local clinics. Adult mosquitoes were collected by space-spraying of living quarters and stables and by cattle bait catches. Mosquito head-thoraces (17,255 specimens) were tested for Plasmodium falciparum and P. vivax circumsporozoite protein (CSP) using enzyme-linked immunosorbent assay. The recorded incidence of P. vivax and P. falciparum was 199 and 41 episodes per 1000 person years, respectively. Twelve species of anopheline were recorded; Anopheles stephensi comprised 82% and A. culicifacies 5%. Eight species tested positive for CSP: A. stephensi, A. culicifacies, A. fluviatilus, A. annularis, A. pulcherrimus, A. maculatus, A. splendidus and A. superpictus. Among infected mosquitoes 46% were positive for P. falciparum, 45% for P. vivax VK-247, and 9% for P. vivax PV-210. Estimates of the feeding rates of infective vectors on humans indicated that A. stephensi would contribute 76% of infective bites, A. fluviatilis and A. pulcherrimus 7% each, and A. culicifacies and A. superpictus 3% each. The overall infective vector feeding rate correlated with the P. vivax incidence rate in the human population. The conventional view of A. culicifacies being the main rural vector and A. stephensi important only in urban settings needs to be reconsidered in western outreaches of the Indo-Pakistan subcontinent.

Item Type: Article
Keywords: malaria, mosquitoes, Anopheles stephensi, Anopheles, culicifacies, Afghanistan, Plasmodium-falciparum, sri-lanka, pakistan, culicidae, diptera, chloroquine, sporozoites, resistance, mosquitos, elisa, Afghanistan, epidemiology, Animal, Anopheles, parasitology, Enzyme-Linked Immunosorbent Assay, Human, Incidence, Insect Vectors, parasitology, Malaria, Falciparum, epidemiology, transmission, Malaria, Vivax, epidemiology, transmission, Plasmodium falciparum, isolation & purification, Plasmodium vivax, isolation & purification, Rural Health, Seasons, Support, Non-U.S. Gov't
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
Research Centre: Malaria Centre
PubMed ID: 12625136
Web of Science ID: 181165200011
URI: http://researchonline.lshtm.ac.uk/id/eprint/17467

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