Evaluation of Binax NOW Streptococcus pneumoniae urinary antigen test in children in a community with a high carriage rate of pneumococcus


Adegbola, RA; Obaro, SK; Biney, E; Greenwood, BM; (2001) Evaluation of Binax NOW Streptococcus pneumoniae urinary antigen test in children in a community with a high carriage rate of pneumococcus. The Pediatric infectious disease journal, 20 (7). pp. 718-9. ISSN 0891-3668

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Abstract

Pneumococcal antigen was present in urine from 49 of 102 well Gambian children. Eighty-nine of the 102 were nasopharyngeal carriers of pneumococci. The positive predictive value for carriage was 96%, and the negative predictive value was 22%. The test is not useful for predicting etiology of disease in populations with a high rate of nasopharyngeal carriage of pneumococci.

Item Type: Article
Keywords: Streptococcus pneumoniae, nasopharyngeal colonization, urinary, antigen detection, Binax NOW, Gambian children, etiology, Antigens, Bacterial, urine, Carrier State, urine, Child, Preschool, Community-Acquired Infections, diagnosis, urine, Gambia, Human, Nasopharynx, microbiology, Pneumococcal Infections, diagnosis, immunology, urine, Predictive Value of Tests, Streptococcus pneumoniae, immunology, isolation & purification
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
PubMed ID: 11465850
Web of Science ID: 169855300018
URI: http://researchonline.lshtm.ac.uk/id/eprint/17206

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