Malaria crystalloids: specialized structures for parasite transmission?


Dessens, JT; Saeed, S; Tremp, AZ; Carter, V; (2011) Malaria crystalloids: specialized structures for parasite transmission? Trends in parasitology, 27 (3). pp. 106-10. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2010.12.004

[img]
Preview
Text - Published Version
License:

Download (836kB) | Preview

Abstract

Malaria parasites possess many unique subcellular structures and organelles that are essential for the successful completion of the complex life cycle of Plasmodium in the vertebrate host and mosquito vector. Among these are the crystalloids: transient structures whose presence is restricted to the mosquito-specific ookinete and young oocyst stages of the parasite. Nearly five decades after they were first described, the crystalloids are back in the spotlight, with recent discoveries pointing to an important role in protein trafficking and sporozoite transmission that could be exploited as new targets for control of malaria transmission.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Pathogen Molecular Biology
Research Centre: Malaria Centre
PubMed ID: 21237711
Web of Science ID: 288846200005
URI: http://researchonline.lshtm.ac.uk/id/eprint/1692

Statistics


Download activity - last 12 months
Downloads since deposit
218Downloads
294Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item