Rates of adverse reactions to first and second doses of BCG vaccination: results of a large community trial in Brazilian schoolchildren


Dourado, I; Rios, MH; Pereira, SMM; Cunha, SS; Ichihara, MY; Goes, JCL; Rodrigues, LC; Bierrenbach, AL; Barreto, ML; (2003) Rates of adverse reactions to first and second doses of BCG vaccination: results of a large community trial in Brazilian schoolchildren. The international journal of tuberculosis and lung disease , 7 (4). pp. 399-402. ISSN 1027-3719

Full text not available from this repository.

Abstract

OBJECTIVE: To evaluate the incidence of adverse reactions to first and second bacille Calmette-Guérin (BCG) vaccination in schoolchildren. SETTING AND DESIGN: Enhanced surveillance in a Brazilian trial. Suspected reactions were reported to a nurse who visited cases and completed a standard form. RESULTS: Among 71341 schoolchildren studied, 33 reactions were reported. Of these, 25 fulfilled the criteria, resulting in a rate of one per 2854 vaccinations, with no deaths or BCG-osis. Reactions to second doses were more common than to first BCG vaccinations, but this difference was not statistically significant. CONCLUSIONS: Adverse reactions to a second dose of BCG may be more frequent than reactions to a first dose, but they are still rare events.

Item Type: Article
Keywords: BCG vaccine, adverse reactions, BCG-REVAC, Tuberculosis
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Centre for Global Non-Communicable Diseases (NCDs)
Vaccine Centre
PubMed ID: 12729348
Web of Science ID: 182127700017
URI: http://researchonline.lshtm.ac.uk/id/eprint/16536

Statistics


Download activity - last 12 months
Downloads since deposit
0Downloads
312Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item