Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms?


Müller, I; Munder, M; Kropf, P; Hänsch, GM; (2009) Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms? Trends in immunology, 30 (11). pp. 522-30. ISSN 1471-4906 DOI: https://doi.org/10.1016/j.it.2009.07.007

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Abstract

Polymorphonuclear neutrophils (PMN) are linked invariably to the innate immune response, particularly to the defence against bacterial infection. T lymphocytes are studied mainly in virus infections, the defence against tumours, the development and progression of chronic inflammatory processes, in autoimmune phenomena and in materno-fetal tolerance. There is, however, increasing evidence for communication and interactions between PMN and T cells that we discuss here in the context of different physiological and pathological conditions, including acute and chronic inflammatory disease, defence against tumours, and maintenance of pregnancy.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection
PubMed ID: 19775938
Web of Science ID: 271923500003
URI: http://researchonline.lshtm.ac.uk/id/eprint/1641

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