The diagnostic implications of the separation of Entamoeba histolytica and Entamoeba dispar

Ackers, JP; (2002) The diagnostic implications of the separation of Entamoeba histolytica and Entamoeba dispar. Journal of biosciences, 27 (6). pp. 573-578. ISSN 0250-5991

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Abstract

For much of the last hundred years most cases of amoebiasis have been diagnosed by light microscopy. Only relatively recently have we become aware that this technique is usually incapable of distinguishing between two species - Entamoeba histolytica and E. dispar - only the first of which is a pathogen. The implications of this for patient management and, even more, for the validity of epidemiological surveys, are only slowly being addressed. What is clear is that methods are urgently required to distinguish between infections with these two species and this review attempts to summarise some of those, which have been developed to meet this need.

Item Type: Article
Keywords: amoebiasis, antigen detection, Entamoeba dispar, Entamoeba, histolytica, diagnosis, polymerase chain reaction, Polymerase-chain-reaction, amebic liver-abscess, linked-, immunosorbent-assay, adherence lectin, stool specimens, monoclonal-antibodies, direct amplification, antigen-detection, differentiation, dna
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Pathogen Molecular Biology
Web of Science ID: 179604900005
URI: http://researchonline.lshtm.ac.uk/id/eprint/16257

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