Lifestyle behaviours and quality-adjusted life years in middle and older age

Myint, PK; Smith, RD; Luben, RN; Surtees, PG; Wainwright, NWJ; Wareham, NJ; Khaw, KT; (2011) Lifestyle behaviours and quality-adjusted life years in middle and older age. Age and ageing, 40 (5). pp. 589-595. ISSN 0002-0729 DOI:

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Methods: a population-based study was conducted in 13,358 men and women who participated in the European Prospective Investigation into Cancer (EPIC)-Norfolk (baseline 1993-97). A score of 1 was given to each of non-smoking, physically not inactive, moderate alcohol consumption (1-14 units) and consumption of at least five portions of fruit and vegetables (vitamin C level >= 50 mu mol/l). Short-Form Six-Dimension (SF-6D) health utility index scores were derived from the SF-36. QALYs were estimated up to follow-up (July 2007). Results: a total of 13,358 men and women were eligible to be included in the study (aged 40-79 years at baseline). A total of 12,921 people were alive at follow-up (117, 784 person-years). Mean follow-up period was similar to 11.5 years. 437 (4.4% of men and 2.4% of women) died. The death rate was 6.5 times higher in people with health behaviour score 0 compared with those who scored 4 (8.4 versus 1.3%). People with higher scores had significantly higher QALYs. Conclusion: our findings support the view that modifiable lifestyle factors are an important component in health improvement.

Item Type: Article
Keywords: quality-adjusted life year (QALY), lifestyle behaviours, quality-of-life, SF-36, SF-6D, elderly, cancer epic-norfolk, physical-activity questionnaire, sf-36 health, survey, prospective population, functional health, of-life, women, men, mortality, cohort, ieto l, 2003, v1, p80
Faculty and Department: Faculty of Public Health and Policy
Research Centre: Centre for Global Non-Communicable Diseases (NCDs)
PubMed ID: 21616956
Web of Science ID: 293904200012


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