IL-18 regulates intestinal mastocytosis and Th2 cytokine production independently of IFN-gamma during Trichinella spiralis infection

Helmby, H; Grencis, RK; (2002) IL-18 regulates intestinal mastocytosis and Th2 cytokine production independently of IFN-gamma during Trichinella spiralis infection. Journal of immunology (Baltimore, Md, 169 (5). pp. 2553-60. ISSN 0022-1767 DOI: https://doi.org/10.4049/jimmunol.169.5.2553

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https://doi.org/10.4049/jimmunol.169.5.2553

Abstract

Item Type Article
Keywords Animal, Cell Movement/genetics/immunology, Cells, Cultured, Comparative Study, Cytokines/antagonists & inhibitors/*biosynthesis/secretion, Immunity, Natural/genetics, Injections, Intraperitoneal, Interferon Type II/antagonists & inhibitors/*physiology/secretion, Interleukin-10/antagonists & inhibitors/genetics/secretion, Interleukin-13/antagonists & inhibitors/genetics/secretion, Interleukin-18/deficiency/genetics/*physiology, Interleukin-4/secretion, Interleukin-9/antagonists & inhibitors/genetics, Intestinal Diseases, Parasitic/genetics/*immunology/parasitology, Intestinal Mucosa/immunology/parasitology, Jejunal Diseases/genetics/immunology/parasitology, Lymph Nodes/immunology/pathology/secretion, Male, Mast Cells/immunology, Mastocytosis/genetics/*immunology/parasitology/prevention & control, Mesentery, Mice, Mice, Inbred C57BL, Mice, Knockout, Muscle, Skeletal/immunology/parasitology, RNA, Messenger/antagonists & inhibitors, Recombinant Proteins/administration & dosage, Support, Non-U.S. Gov't, Th1 Cells/immunology/secretion, Th2 Cells/*immunology/secretion, Trichinella spiralis/growth & development/*immunology, Trichinosis/genetics/*immunology/parasitology, Animal, Cell Movement, genetics, immunology, Cells, Cultured, Comparative Study, Cytokines, antagonists & inhibitors, biosynthesis, secretion, Immunity, Natural, genetics, Injections, Intraperitoneal, Interferon Type II, antagonists & inhibitors, physiology, secretion, Interleukin-10, antagonists & inhibitors, genetics, secretion, Interleukin-13, antagonists & inhibitors, genetics, secretion, Interleukin-18, deficiency, genetics, physiology, Interleukin-4, secretion, Interleukin-9, antagonists & inhibitors, genetics, Intestinal Diseases, Parasitic, genetics, immunology, parasitology, Intestinal Mucosa, immunology, parasitology, Jejunal Diseases, genetics, immunology, parasitology, Lymph Nodes, immunology, pathology, secretion, Male, Mast Cells, immunology, Mastocytosis, genetics, immunology, parasitology, prevention & control, Mesentery, Mice, Mice, Inbred C57BL, Mice, Knockout, Muscle, Skeletal, immunology, parasitology, RNA, Messenger, antagonists & inhibitors, Recombinant Proteins, administration & dosage, Support, Non-U.S. Gov't, Th1 Cells, immunology, secretion, Th2 Cells, immunology, secretion, Trichinella spiralis, growth & development, immunology, Trichinosis, genetics, immunology, parasitology
Faculty and Department Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection
Research Centre Neglected Tropical Diseases Network
PubMed ID 12193725
ISI 177594100040

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