Progressive increase in antimicrobial resistance among invasive isolates of Haemophilus influenzae obtained from children admitted to a hospital in Kilifi, Kenya, from 1994 to 2002.
Scott, J Anthony G;
Mwarumba, Salim;
Ngetsa, Caroline;
Njenga, Salome;
Lowe, Brett S;
Slack, Mary PE;
Berkley, James A;
Mwangi, Isaiah;
Maitland, Kathryn;
English, Mike;
+1 more...Marsh, Kevin;
(2005)
Progressive increase in antimicrobial resistance among invasive isolates of Haemophilus influenzae obtained from children admitted to a hospital in Kilifi, Kenya, from 1994 to 2002.
Antimicrobial agents and chemotherapy, 49 (7).
pp. 3021-3024.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.49.7.3021-3024.2005
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Etest susceptibilities to amoxicillin, chloramphenicol, and trimethoprim-sulfamethoxazole of 240 invasive isolates of Haemophilus influenzae cultured from children in rural Kenya were 66%, 66%, and 38%, respectively. Resistance increased markedly over 9 years and was concentrated among serotype b isolates. In Africa, the increasing cost of treating resistant infections supports economic arguments for prevention through conjugate H. influenzae type b immunization.