Progressive increase in antimicrobial resistance among invasive isolates of Haemophilus influenzae obtained from children admitted to a hospital in Kilifi, Kenya, from 1994 to 2002.


Scott, JA; Mwarumba, S; Ngetsa, C; Njenga, S; Lowe, BS; Slack, MP; Berkley, JA; Mwangi, I; Maitland, K; English, M; Marsh, K; (2005) Progressive increase in antimicrobial resistance among invasive isolates of Haemophilus influenzae obtained from children admitted to a hospital in Kilifi, Kenya, from 1994 to 2002. Antimicrobial agents and chemotherapy, 49 (7). pp. 3021-4. ISSN 0066-4804 DOI: 10.1128/AAC.49.7.3021-3024.2005

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Abstract

Etest susceptibilities to amoxicillin, chloramphenicol, and trimethoprim-sulfamethoxazole of 240 invasive isolates of Haemophilus influenzae cultured from children in rural Kenya were 66%, 66%, and 38%, respectively. Resistance increased markedly over 9 years and was concentrated among serotype b isolates. In Africa, the increasing cost of treating resistant infections supports economic arguments for prevention through conjugate H. influenzae type b immunization.

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Antimicrobial Resistance Centre (AMR)
PubMed ID: 15980390
Web of Science ID: 230181800069
URI: http://researchonline.lshtm.ac.uk/id/eprint/1440337

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