Long chain polyunsaturated fatty acids (LC-PUFA) and perinatal development


Koletzko, B; Agostoni, C; Carlson, SE; Clandinin, T; Hornstra, G; Neuringer, M; Uauy, R; Yamashiro, Y; Willatts, P; (2001) Long chain polyunsaturated fatty acids (LC-PUFA) and perinatal development. Acta paediatrica (Oslo, Norway, 90 (4). pp. 460-4. ISSN 0803-5253 DOI: https://doi.org/10.1080/080352501750126492

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Abstract

This paper reports on the conclusions of a workshop on the role of long chain polyunsaturated fatty acids (LC-PUFA) in maternal and child health. The attending investigators involved in the majority of randomized trials examining LC-PUFA status and functional outcomes summarize the current knowledge in the field and make recommendations for dietary practice. Only studies published in full or in abstract form were used as our working knowledge base. Conclusions: For healthy infants we recommend and strongly support breastfeeding as the preferred method of feeding, which supplies preformed LC-PUFA. Infant formulas for term infants should contain at least 0.2% of total fatty acids as docosahexaenoic acid (DHA) and 0.35% as arachidonic acid (AA). Since preterm infants are born with much less total body DHA and AA, we suggest that preterm infant formulas should include at least 0.35% DHA and 0.4% AA. Higher levels might confer additional benefits and should be further investigated because optimal dietary intakes for term and preterm infants remain to be defined. For pregnant and lactating women we consider it premature to recommend specific LC-PUFA intakes. However, it seems prudent for pregnant and lactating women to include some food sources of DHA in their diet in view of their assumed increase in LC-PUFA demand and the relationship between maternal and foetal DHA status.

Item Type: Article
Keywords: Animals, Breast Feeding, Dietary Supplements, Fatty Acids, Unsaturated, Female, Fetus, Humans, Lactation, Pregnancy, Research Support, Non-U.S. Gov't, Vision, Animals, Breast Feeding, Dietary Supplements, Fatty Acids, Unsaturated, metabolism, physiology, Female, Fetus, physiology, Humans, Lactation, physiology, Pregnancy, physiology, Research Support, Non-U.S. Gov't, Vision, physiology
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Population Health (2012- ) > Dept of Nutrition and Public Health Interventions Research (2003-2012)
Faculty of Epidemiology and Population Health > Dept of Population Health (2012- )
Research Centre: Centre for Global Non-Communicable Diseases (NCDs)
PubMed ID: 11332943
Web of Science ID: 168407400023
URI: http://researchonline.lshtm.ac.uk/id/eprint/12855

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