The geographical distribution and burden of trachoma in Africa.


Smith, JL; Flueckiger, RM; Hooper, PJ; Polack, S; Cromwell, EA; Palmer, SL; Emerson, PM; Mabey, DC; Solomon, AW; Haddad, D; Brooker, SJ; (2013) The geographical distribution and burden of trachoma in Africa. PLoS neglected tropical diseases, 7 (8). e2359. ISSN 1935-2727 DOI: https://doi.org/10.1371/journal.pntd.0002359

[img]
Preview
Text - Published Version
License:

Download (809kB) | Preview

Abstract

BACKGROUND There remains a lack of epidemiological data on the geographical distribution of trachoma to support global mapping and scale up of interventions for the elimination of trachoma. The Global Atlas of Trachoma (GAT) was launched in 2011 to address these needs and provide standardised, updated and accessible maps. This paper uses data included in the GAT to describe the geographical distribution and burden of trachoma in Africa. METHODS Data assembly used structured searches of published and unpublished literature to identify cross-sectional epidemiological data on the burden of trachoma since 1980. Survey data were abstracted into a standardised database and mapped using geographical information systems (GIS) software. The characteristics of all surveys were summarized by country according to data source, time period, and survey methodology. Estimates of the current population at risk were calculated for each country and stratified by endemicity class. RESULTS At the time of writing, 1342 records are included in the database representing surveys conducted between 1985 and 2012. These data were provided by direct contact with national control programmes and academic researchers (67%), peer-reviewed publications (17%) and unpublished reports or theses (16%). Prevalence data on active trachoma are available in 29 of the 33 countries in Africa classified as endemic for trachoma, and 1095 (20.6%) districts have representative data collected through population-based prevalence surveys. The highest prevalence of active trachoma and trichiasis remains in the Sahel area of West Africa and Savannah areas of East and Central Africa and an estimated 129.4 million people live in areas of Africa confirmed to be trachoma endemic. CONCLUSION The Global Atlas of Trachoma provides the most contemporary and comprehensive summary of the burden of trachoma within Africa. The GAT highlights where future mapping is required and provides an important planning tool for scale-up and surveillance of trachoma control.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Faculty of Infectious and Tropical Diseases > Dept of Disease Control
Research Centre: Neglected Tropical Diseases Network
The International Centre for Evidence in Disability
International Centre for Eye Health
PubMed ID: 23951378
Web of Science ID: 323941500024
URI: http://researchonline.lshtm.ac.uk/id/eprint/1152816

Statistics


Download activity - last 12 months
Downloads since deposit
225Downloads
355Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item