A brief history of economic evaluation for human papillomavirus vaccination policy.

Beutels, P; Jit, M; (2010) A brief history of economic evaluation for human papillomavirus vaccination policy. Sexual health, 7 (3). pp. 352-8. ISSN 1448-5028 DOI: https://doi.org/10.1071/SH10018

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BACKGROUND: This commentary discusses key issues for health economic evaluation and modelling, applied to human papillomavirus (HPV) vaccine programs. METHODS: We outline some of the specific features of HPV disease and vaccination, and associated policy questions in light of a literature search for economic evaluations on HPV vaccination. RESULTS: We observe that some policy questions could not be reliably addressed by many of the 43 published economic evaluations we found. Despite this, policy making on universal HPV vaccination followed shortly after vaccine licensure in many developed countries, so the role economic evaluation played in informing these decisions (pre-dating 2008) seems to have been fairly limited. For more recent decisions, however, economic evaluation is likely to have been used more widely and more intensively. CONCLUSIONS: We expect future cost-effectiveness analyses to be more instrumental in policy making regarding vaccines covering more HPV types, therapeutic HPV vaccines, and novel diagnostic tests for biomarkers of HPV infection and disease integrated with cervical screening programs.

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Vaccine Centre
PubMed ID: 20719227
Web of Science ID: 281029900022
URI: http://researchonline.lshtm.ac.uk/id/eprint/111801


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