Chapter 28: Studies to assess the long-term efficacy and effectiveness of HPV vaccination in developed and developing countries.


Lehtinen, M; Herrero, R; Mayaud, P; Barnabas, R; Dillner, J; Paavonen, J; Smith, PG; (2006) Chapter 28: Studies to assess the long-term efficacy and effectiveness of HPV vaccination in developed and developing countries. Vaccine, 24 Suppl 3. S233-41. ISSN 0264-410X DOI: 10.1016/j.vaccine.2006.05.109

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Abstract

We review studies of the implementation of human papillomavirus (HPV) vaccination programmes in developed and developing countries. The review spans the period from establishment of long-term vaccine efficacy follow-up studies, operational research on issues of vaccine preparedness, and relevant predictive modelling studies during the pre-licensure phase to plans of phase IV effectiveness trials, forms of epidemiological surveillance, and further operational research in the post-licensure phase. Much of the research is already ongoing. Depending on the results of the planned immuno bridging studies among HIV-negative and HIV-positive women, further phase III and/or phase IV trials may be warranted.

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Research Centre: Centre for Global Non-Communicable Diseases (NCDs)
Centre for Maternal, Reproductive and Child Health (MARCH)
PubMed ID: 16950012
Web of Science ID: 240470000030
URI: http://researchonline.lshtm.ac.uk/id/eprint/11096

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