Male circumcision as a preventive measure against HIV and other sexually transmitted diseases.


Weiss, HA; (2007) Male circumcision as a preventive measure against HIV and other sexually transmitted diseases. Current opinion in infectious diseases, 20 (1). pp. 66-72. ISSN 0951-7375 DOI: https://doi.org/10.1097/QCO.0b013e328011ab73

Full text not available from this repository. (Request a copy)

Abstract

: In 2005, 4.1 million people were infected with HIV. There is an urgent need to intensify and expand HIV prevention methods. Male circumcision is one of several potential approaches. This review summarizes recent evidence for the potential of male circumcision to prevent HIV and other sexually transmitted infections.<br/> : The first randomized controlled trial of adult male circumcision found a highly significant 60% reduction in HIV incidence among men in the intervention arm. Modelling this effect predicts that widespread implementation of male circumcision could avert 2 million HIV infections over the next decade in sub-Saharan Africa. The biological rationale is that the foreskin increases risk of HIV infection due to the high density of HIV target cells and lack of keratinization of the inner mucosal surface.<br/> : There is strong evidence that male circumcision reduces risk of HIV, syphilis and chancroid. If results are confirmed by two ongoing trials in sub-Saharan Africa, provision of safe male circumcision could be added to HIV prevention packages in high-incidence settings. This would also provide an opportunity for HIV-prevention education and counselling to young men at high risk of infection.<br/>

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Centre for Maternal, Reproductive and Child Health (MARCH)
Tropical Epidemiology Group
PubMed ID: 17197884
Web of Science ID: 243810900011
URI: http://researchonline.lshtm.ac.uk/id/eprint/10652

Statistics


Download activity - last 12 months
Downloads since deposit
0Downloads
302Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item