Young men were at risk of becoming lost to follow-up in a cohort of head-injured adults.


Edwards, P; Fernandes, J; Roberts, I; Kuppermann, N; (2007) Young men were at risk of becoming lost to follow-up in a cohort of head-injured adults. Journal of clinical epidemiology, 60 (4). pp. 417-24. ISSN 0895-4356 DOI: https://doi.org/10.1016/j.jclinepi.2006.06.021

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Abstract

OBJECTIVE: This study is to identify predictors of loss to follow-up among adults with head injury. STUDY DESIGN AND SETTING: A prospective cohort of 1,857 adults enrolled in the Medical Research Council (MRC) CRASH trial known to be alive 2 weeks after head injury. Six-month follow-up was defined as "overdue" if over 6 months late. Patient information collected at enrollment and after 14 days was used to predict overdue follow-up. A random two-thirds of the cohort was analyzed using logistic regression and binary recursive partitioning. The regression model and decision rule derived by recursive partitioning were evaluated using the remaining third. RESULTS: Overdue follow-up was more likely in patients aged 25-34 years (odds ratio, 1.76; 95% confidence interval [CI]=1.18-2.62), victims of assault (1.63; 1.09-2.45), patients independent after 2 weeks (1.79; 1.18-2.72) and patients for whom postcodes (2.36; 1.65-3.39), telephone numbers (1.82; 1.19-2.79) or general practitioners (1.67; 1.16-2.39) were unknown. Binary recursive partitioning specifically identified males aged younger than 43 years to be at risk. CONCLUSION: Successful follow-up in head-injury studies requires patients' postcodes and telephone numbers to be available. Young men remain at risk of becoming lost to follow-up, presenting a challenge for researchers aiming for complete data.

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Population Health (2012- ) > Dept of Nutrition and Public Health Interventions Research (2003-2012)
Faculty of Epidemiology and Population Health > Dept of Population Health (2012- )
Research Centre: Centre for Global Non-Communicable Diseases (NCDs)
PubMed ID: 17346617
Web of Science ID: 245094200015
URI: http://researchonline.lshtm.ac.uk/id/eprint/10335

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