Feasibility of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban cholera-endemic setting in Mozambique


Cavailler, P; Lucas, M; Perroud, V; McChesney, M; Ampuero, S; Guerin, PJ; Legros, D; Nierle, T; Mahoudeau, C; Lab, B; Kahozi, P; Deen, JL; von Seidlein, L; Wang, XY; Puri, M; Ali, M; Clemens, JD; Songane, F; Baptista, A; Ismael, F; Barreto, A; Chaignat, CL; (2006) Feasibility of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban cholera-endemic setting in Mozambique. Vaccine, 24 (22). pp. 4890-5. ISSN 0264-410X DOI: 10.1016/j.vaccine.2005.10.006

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Abstract

We conducted a study to assess the feasibility and the potential vaccine coverage of a mass vaccination campaign using a two-dose oral cholera vaccine in an urban endemic neighbourhood of Beira, Mozambique. The campaign was conducted from December 2003 to January 2004. Overall 98,152 doses were administered, and vaccine coverage of the target population was 58.6% and 53.6% for the first and second rounds, respectively. The direct cost of the campaign, which excludes the price of the vaccine, amounted to slightly over 90,000 dollars, resulting in the cost per fully vaccinated person of 2.09 dollars, which is relatively high. However, in endemic settings where outbreaks are likely to occur, integrating cholera vaccination into the routine activities of the public health system could reduce such costs.

Item Type: Article
Keywords: Administration, Oral, Adolescent, Child, Child, Preschool, Cholera/*epidemiology/prevention & control, Costs and Cost Analysis, Female, Humans, Male, *Mass Immunization/economics, Mozambique/epidemiology, Administration, Oral, Adolescent, Child, Child, Preschool, Cholera, epidemiology, prevention & control, Costs and Cost Analysis, Female, Humans, Male, Mass Immunization, economics, Mozambique, epidemiology
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
Research Centre: Vaccine Centre
PubMed ID: 16298025
Web of Science ID: 238704000023
URI: http://researchonline.lshtm.ac.uk/id/eprint/10268

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